Header Molecular Tumor Diagnostics

Core Unit for Molecular Tumor Diagnostics

The Core Unit for Molecular Tumor Diagnostics (CMTD) is a research facility for the molecular characterization of sporadic and hereditary tumors based on next generation sequencing (NSG) techniques, bioinformatic analysis pipelines and interpretation of the results by experienced molecular pathologists and human geneticists. It is an essential and fundamental interface in the area of translational cancer research and clinical studies. The aim of the CMTD is the fast translation of novel molecular markers into clinical application by making indication-specific multi gene panels available. 

CMTD Workflow

Service features:

  • Complete processing from tumor samples and liquid biopsies to clinical report
  • Evaluation of tumor samples by a pathologist (including assessment of tumor cell content and microdissection). 
  • DNA/RNA preparation with quality assessment. 
  • Enrichment and Sequencing on the NextSeq500 platform. 
  • Data analysis and interpretation by a board certified human geneticist and a board certified (molecular) pathologist (OÄ Prof. Dr. med. Daniela Aust). 
  • Additional molecular genetic analyses as well as immunohistochemistry and fluorescence in situ hybridization (FISH) 
  • Development of customized multi-gene-panels for user specific applications 
  • Consulting for research projects and support with grant applications

Please contact Prof. Dr. med. Daniela Aust for project planning.

NCT Dresden Tumor-Diagnostikgruppe


Alexander Krüger
Laboratory / Technical assistance
Tel.: +49 (0)351 458 16857

Prof. Dr. med. Daniela E. Aust (sporadic tumors)
Tel.: +49 (0) 351 458 3004


Prof. Dr. med. Gustavo Baretton
Director of the institute for pathology
Tel.: +49 (0) 351 458 3000

Prof. Dr. med. Evelin Schröck
Director of the institute for clinical genetics
Tel.: +49 (0) 351 458 5136


Prof. Dr. med. Daniela Aust
Institute for pathology
Tel.: +49 (0)351 458 3004

Dr. Sandra Oster
Tel.: +49 (0)351 458 11854