TATRA

Gastrointestinal tumors
Colorectal cancer
Surgical Studies
The goal of this clinical trial is to learn if the administration of tranexamic acid canreduce the necessity of blood transfusions in adult patients undergoing major abdominalsurgery. It will also inform about safety of tranexamic acid in this setting.The main question it aims to answer is: Does tranexamic acid lower the probability ofreceiving at least one blood transfusion during or after surgery?Participants will compare tranexamic acid o a placebo (a look-alike substance thatcontains no drug) to see if tranexamic acid works to reduce the necessity of a bloodtransfusion.