The analysis of prospective registry data, as a method of translational research, combines controlled, prospective observations with routine patient care. The primary goal of the Cancer-Reg-VT (Pan) research project is to investigate treatment-specific outcomes, care pathways, and quality of care, taking into account potential influencing factors from both patients and providers. It aims to explore questions in the field of clinical and health services research, which are contributed, among others, by physicians at Dresden University Hospital who are directly involved in patient treatment.
Through standardized data collection and consolidation, the project aims to achieve a high degree of harmonization. Primary data on quality of life and secondary data from the hospital information and tumor documentation system, as well as external data will be linked at the individual level. Recruitment will be prospective, but data collection will be conducted prospectively for 5 years and retrospectively for 5 years. This will allow patients in follow-up care at the Dresden University Hospital to be included. Only through data linkage is a comprehensive, longitudinal dataset available for investigating the research questions available. The current project considers colorectal carcinoma, pancreatic carcinoma, and malignant melanoma.
As part of a questionnaire survey, all study participants are regularly surveyed on their quality of life. The standardized, validated, generic QLQ C30 questionnaire of the EORTC is used. Regular follow-up of the survey takes place, with the frequency depending on the specific cancer entity. Clinical data, biodata, histology, imaging data, and billing data are not primarily collected but extracted from the respective systems (e.g., clinical information and tumor documentation systems). Data from the cancer registry and statutory health insurance funds are being newly requested for this project.
The research project Cancer-Reg-VT (Pan) investigates how cancer patients are treated and analyses the outcomes of these treatments. The goal is to evaluate and improve the quality of care by systematically collecting data from routine clinical practice. Both the perspectives of patients and treating physicians are taken into account.
The study combines data from various sources, including questionnaires on quality of life, hospital and tumor documentation systems, as well as external data such as health insurance information. These data are collected over a period of five years, both retrospectively and prospectively. This approach allows the inclusion of patients in follow-up care and enables the analysis of long-term developments.
The focus is on three types of cancer: colorectal cancer, pancreatic cancer, and malignant melanoma. The findings aim to identify barriers and facilitating factors for innovative cancer diagnostics and therapies, ultimately improving patient care
