The purpose of this study is to compare how long the participants are disease-free(progression-free survival) when treated with amivantamab and chemotherapy with5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin, oxaliplatin(mFOLFOX6) or 5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin, andirinotecan hydrochloride (FOLFIRI) versus cetuximab and mFOLFOX6 or FOLFIRI in adultparticipants with Kirsten rat sarcoma viral oncogene homolog (KRAS)/ Neuroblastoma RASviral oncogene homolog (NRAS) and v-Raf murine sarcoma viral oncogene homolog B1 (BRAF)wild type (WT) unresectable or metastatic left-sided colorectal cancer.
The purpose of this study is to compare how long the participants are disease-free(progression-free survival) when treated with amivantamab and chemotherapy with5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin, oxaliplatin(mFOLFOX6) or 5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin, andirinotecan hydrochloride (FOLFIRI) versus cetuximab and mFOLFOX6 or FOLFIRI in adultparticipants with Kirsten rat sarcoma viral oncogene homolog (KRAS)/ Neuroblastoma RASviral oncogene homolog (NRAS) and v-Raf murine sarcoma viral oncogene homolog B1 (BRAF)wild type (WT) unresectable or metastatic left-sided colorectal cancer.
